منابع مشابه
Beta-blockers for hypertension
BACKGROUND Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardial infarction. Beta-blockers were thought to have similar beneficial effects when used as first-line therapy for hypertension. Howev...
متن کاملCochrane corner: beta-blockers for hypertension
BaCkground Beta-blockers refer to an assorted group of medications that block the action of endogenous catecholamines on beta-adrenergic receptors. The β1 and β2 receptors are the primary beta-adrenergic receptors in the human cardiovascular system. Betablockers differ in their β1/β2-receptor selectivity and vasodilatory properties. Based on this diversity, beta-blockers have been categorised i...
متن کاملAmlodipine and valsartan: calcium channel blockers/angiotensin II receptor blockers combination for hypertension
10.2217/14750708.4.1.31 © 20 Despite the availability of numerous antihypertensive agents, many patients with hypertension fail to achieve the blood pressure goals set out in current guidelines. These patients remain at a high risk of cardiovascular morbidity and mortality and require effective treatment options to reduce that risk. Current guidelines recognize that many patients require multip...
متن کامل35 Beta Blockers in Hypertension — Losing Ground ?
Hypertension is a common condition in developed and developing nations, associated with cardiovascular complications and end organ damage, and yet its etiology remains largely elusive. It has long been recognized that satisfactory control of blood pressure reduces cardiovascular complications. Early trials, before the advent of drugs acting on the renin-aldosterone system, (RAS) revealed the th...
متن کاملβ blockers in hypertension and cardiovascular disease
β blockers are useful in managing angina and reducing mortality after myocardial infarction and in heart failure. They probably reduce cardiovascular events in high risk surgery and retard the progression of atherosclerosis. In younger patients, β blockers should remain first line antihypertensives, together with diuretics, calcium channel blockers, angiotensin converting enzymes, and adrenergi...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2007
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.1060199